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DNA breakage and cell cycle checkpoint abrogation induced by a therapeutic thiopurine and UVA radiation

The frequency of squamous cell skin carcinoma in organ transplant patients is around 100-fold higher than normal. This dramatic example of therapy-related cancer reflects exposure to sunlight and to immunosuppressive drugs. Here we demonstrate that the interaction between low doses of UVA, the major...

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Sonraí Bibleagrafaíochta
Main Authors: Brem, Reto, Li, Feng, Montaner, Beatriz, Reelfs, Olivier, Karran, Peter
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901207/
https://ncbi.nlm.nih.gov/pubmed/20440263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.140
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