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X-linked Tumor Suppressors: Perplexing Inheritance, a unique Therapeutic Opportunity
Unlike autosomal genes, the majority of X-linked genes are subject to dosage compensation. As a result, female tissues are comprised of cells exclusively expressing X-linked genes from one or the other parent. The implication of having only one allele of active X-linked genes in cancer pathogenesis,...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901104/ https://ncbi.nlm.nih.gov/pubmed/20434787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2010.03.004 |
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