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Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function

Acute-phase proteins (APPs) are an evolutionarily conserved family of proteins produced mainly in the liver in response to infection and inflammation. Despite vast pro- and antiinflammatory properties ascribed to individual APPs, their collective function during infections remains poorly defined. Us...

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Hlavní autoři: Sander, Leif E., Sackett, Sara Dutton, Dierssen, Uta, Beraza, Naiara, Linke, Reinhold P., Müller, Michael, Blander, J. Magarian, Tacke, Frank, Trautwein, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901069/
https://ncbi.nlm.nih.gov/pubmed/20530204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091474
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