IL-10/TGF-β–Modified Macrophages Induce Regulatory T Cells and Protect against Adriamycin Nephrosis

IL-10/TGF-β–modified macrophages, a subset of activated macrophages, produce anti-inflammatory cytokines, suggesting that they may protect against inflammation-mediated injury. Here, macrophages modified ex vivo by IL-10/TGF-β (IL-10/TGF-β Μ2) significantly attenuated renal inflammation, structural...

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Hlavní autoři: Cao, Qi, Wang, Yiping, Zheng, Dong, Sun, Yan, Wang, Ya, Lee, Vincent W.S., Zheng, Guoping, Tan, Thian Kui, Ince, Jon, Alexander, Stephen I., Harris, David C.H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2010
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900959/
https://ncbi.nlm.nih.gov/pubmed/20299353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009060592
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