APOE/C1/C4/C2 hepatic control region polymorphism influences plasma apoE and LDL cholesterol levels

We characterized 102 kb of chromosome 19 containing the apolipoprotein (APO) E/C1/C4/C2 cluster and two flanking genes for common DNA variants associated with plasma low-density lipoprotein cholesterol (LDL-C) level. DNA variants were identified by comparing sequences of 48 haploid hybrid cell lines...

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Autores principales: Klos, Kathy, Shimmin, Lawrence, Ballantyne, Christie, Boerwinkle, Eric, Clark, Andrew, Coresh, Josef, Hanis, Craig, Liu, Kiang, Sayre, Scott, Hixson, James
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2008
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900905/
https://ncbi.nlm.nih.gov/pubmed/18378515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn101
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