Physiological and glycomic characterization of N-acetylglucosaminyltransferase-IVa and -IVb double deficient mice

N-Acetylglucosaminyltransferase-IV (GnT-IV) has two isoenzymes, GnT-IVa and GnT-IVb, which initiate the GlcNAcβ1-4 branch synthesis on the Manα1-3 arm of the N-glycan core thereby increasing N-glycan branch complexity and conferring endogenous lectin binding epitopes. To elucidate the physiological...

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Detalhes bibliográficos
Main Authors: Takamatsu, Shinji, Antonopoulos, Aristotelis, Ohtsubo, Kazuaki, Ditto, David, Chiba, Yasunori, Le, Dzung T., Morris, Howard R., Haslam, Stuart M., Dell, Anne, Marth, Jamey D., Taniguchi, Naoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Regular Manuscripts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900882/
https://ncbi.nlm.nih.gov/pubmed/20015870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwp200
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