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Endogenous antibodies promote rapid myelin clearance and effective axon regeneration after nerve injury

Degenerating myelin inhibits axon regeneration and is rapidly cleared after peripheral (PNS) but not central nervous system (CNS) injury. To better understand mechanisms underlying rapid PNS myelin clearance, we tested the potential role of the humoral immune system. Here, we show that endogenous an...

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Autors principals: Vargas, Mauricio E., Watanabe, Junryo, Singh, Simar J., Robinson, William H., Barres, Ben A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900702/
https://ncbi.nlm.nih.gov/pubmed/20547838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001948107
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