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Mapping of cerebral oxidative metabolism with MRI

Using a T(1ρ) MRI based indirect detection method, we demonstrate the detection of cerebral oxidative metabolism and its modulation by administration of the mitochondrial uncoupling agent 2,4-dinitrophenol (DNP) in a large animal model with minimum utilization of [Image: see text] gas. The study was...

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Main Authors: Mellon, Eric A., Beesam, R. Shashank, Elliott, Mark A., Reddy, Ravinder
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900671/
https://ncbi.nlm.nih.gov/pubmed/20547874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006951107
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