Facilitated Phospholipid Translocation in Vesicles and Nucleated Cells Using Synthetic Small Molecule Scramblases

A series of sixteen synthetic scramblase candidates were prepared from a tris(aminoethyl)amine (TREN) scaffold and evaluated for ability to facilitate translocation of fluorescent phospholipid probes across vesicle membranes and endogenous phosphatidylserine across the plasma membrane of nucleated c...

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Main Authors: DiVittorio, Kristy M., Hofmann, Frank T., Johnson, James R., Abu-Esba, Lica, Smith, Bradley D.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900633/
https://ncbi.nlm.nih.gov/pubmed/19028426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.11.011
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