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Altered cortical CDC42 signaling pathways in schizophrenia: Implications for dendritic spine deficits
BACKGROUND: Spine density on the basilar dendrites of pyramidal neurons is lower in layer 3, but not in layers 5-6, in the dorsolateral prefrontal cortex (DLPFC) of subjects with schizophrenia. The expression of CDC42 (cell division cycle 42), a RhoGTPase which regulates the outgrowth of the actin c...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900524/ https://ncbi.nlm.nih.gov/pubmed/20385374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.02.016 |
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