Trigeminal antihyperalgesic effect of intranasal carbon dioxide

AIMS: Clinical studies demonstrate attenuation of trigeminal-related pain states such as migraine by intranasal CO(2) application. This study investigated the underlying mechanisms of this observation and its potential use to reverse trigeminal pain and hypersensitivity. MAIN METHODS: We used a beha...

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Bibliographic Details
Main Authors: Tzabazis, Alexander Z., Niv, Sharon H., Manering, Neil A., Klyukinov, Mikhail, Cuellar, Jason M., Bhatnagar, Anish, Yeomans, David C.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900516/
https://ncbi.nlm.nih.gov/pubmed/20561904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2010.05.013
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