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AGE-DEPENDENT EFFECTS OF κ-OPIOID RECEPTOR STIMULATION ON COCAINE-INDUCED STEREOTYPED BEHAVIORS AND DOPAMINE OVERFLOW IN THE CAUDATE-PUTAMEN: AN IN VIVO MICRODIALYSIS STUDY

κ-Opioid receptor stimulation attenuates psychostimulant-induced increases in extracellular dopamine in the caudate-putamen (CPu) and nucleus accumbens of adult rats, while reducing cocaine-induced locomotor activity and stereotyped behaviors. Because κ-opioid receptor agonists (e.g., U50,488 or U69...

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Detalhes bibliográficos
Main Authors: Cortez, A. M., Charntikov, S., Der-Ghazarian, T., Horn, L. R., Crawford, C. A., McDougall, S. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900406/
https://ncbi.nlm.nih.gov/pubmed/20435099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.04.052
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