Higher Serotonin 1A Binding in a Second Major Depression Cohort: Modeling and Reference Region Considerations

BACKGROUND: Serotonin 1A receptors (5-HT(1A)) are implicated in major depressive disorder (MDD). We previously reported higher 5-HT(1A) binding potential (BP(F)=B(avail)/K(D)) in antidepressant naïve MDD subjects compared to controls while other studies report lower BP(ND)(BP(ND)=f(ND)B(avail)/K(D))...

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Main Authors: Parsey, Ramin V., Ogden, R. Todd, Miller, Jeffrey M., Tin, Adrienne, Hesselgrave, Natalie, Goldstein, Ellen, Mikhno, Arthur, Milak, Matthew, Zanderigo, Francesca, Sullivan, Gregory M., Oquendo, Maria A., Mann, J. John
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900398/
https://ncbi.nlm.nih.gov/pubmed/20497898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.03.023
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