Loss of limbic system-associated membrane protein leads to reduced hippocampal mineralocorticoid receptor expression, impaired synaptic plasticity and spatial memory deficit

BACKGROUND: The limbic system-associated membrane protein (LAMP) promotes development of neurons of limbic origin. We have previously shown that genetic deletion of LAMP results in heightened reactivity to novelty and reduced anxiety-like behaviors in mice. Here, we demonstrate a critical role of LA...

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Autores principales: Qiu, Shenfeng, Champagne, Danielle L., Peters, Melinda, Catania, Elizabeth H., Weeber, Edwin J., Levitt, Pat, Pimenta, Aurea F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900390/
https://ncbi.nlm.nih.gov/pubmed/20385375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2010.02.013
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