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Valproic Acid Induces Notch1 Signaling in Small Cell Lung Cancer Cells
BACKGROUND: Small cell lung cancer (SCLC) is an aggressive malignancy. Current treatments yield dismal survival rates. We have previously demonstrated that histone deacetylase (HDAC) inhibitors can inhibit neuroendocrine tumor growth. Activation of the Notch1 signaling pathway also impairs SCLC cell...
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Principais autores: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900385/ https://ncbi.nlm.nih.gov/pubmed/18570928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2008.03.008 |
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