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Learning a Weighted Sequence Model of the Nucleosome Core and Linker Yields More Accurate Predictions in Saccharomyces cerevisiae and Homo sapiens

DNA in eukaryotes is packaged into a chromatin complex, the most basic element of which is the nucleosome. The precise positioning of the nucleosome cores allows for selective access to the DNA, and the mechanisms that control this positioning are important pieces of the gene expression puzzle. We d...

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Detalhes bibliográficos
Main Authors: Reynolds, Sheila M., Bilmes, Jeff A., Noble, William Stafford
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900294/
https://ncbi.nlm.nih.gov/pubmed/20628623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000834
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