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Large-Scale Analysis of Network Bistability for Human Cancers

Protein–protein interaction and gene regulatory networks are likely to be locked in a state corresponding to a disease by the behavior of one or more bistable circuits exhibiting switch-like behavior. Sets of genes could be over-expressed or repressed when anomalies due to disease appear, and the ci...

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Main Authors: Shiraishi, Tetsuya, Matsuyama, Shinako, Kitano, Hiroaki
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900289/
https://ncbi.nlm.nih.gov/pubmed/20628618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000851
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