Activated Notch1 Target Genes during Embryonic Cell Differentiation Depend on the Cellular Context and Include Lineage Determinants and Inhibitors

BACKGROUND: Notch receptor signaling controls developmental cell fates in a cell-context dependent manner. Although Notch signaling directly regulates transcription via the RBP-J/CSL DNA binding protein, little is known about the target genes that are directly activated by Notch in the respective ti...

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Detalhes bibliográficos
Main Authors: Meier-Stiegen, Franziska, Schwanbeck, Ralf, Bernoth, Kristina, Martini, Simone, Hieronymus, Thomas, Ruau, David, Zenke, Martin, Just, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900208/
https://ncbi.nlm.nih.gov/pubmed/20628604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011481
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