Effects of Family History and APOE ε4 Status on Cognitive Decline in the Absence of AD: The Cache County Study

CONTEXT: Studies have shown that the APOE ε4 genotype is associated with cognitive decline and increased risk of Alzheimer’s dementia (AD). Other genes are probably associated with both outcomes. Family history of AD (FhxAD) may represent genetic factors or shared environmental factors that increase...

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Main Authors: Hayden, Kathleen M., Zandi, Peter P., West, Nancy A., Tschanz, JoAnn T., Norton, Maria C., Corcoran, Chris, Breitner, John C. S., Welsh-Bohmer, Kathleen A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900192/
https://ncbi.nlm.nih.gov/pubmed/19901170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2009.237
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