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Methylnaltrexone: the evidence for its use in the management of opioid-induced constipation

INTRODUCTION: Constipation is a distressing side effect of opioid treatment, being so irksome in some cases that patients would rather suffer the pain than the side effect of opioid analgesics. Stool softeners or stimulating laxatives are often ineffective or even aggravate the situation. A new effi...

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Autors principals: Deibert, Peter, Xander, Carola, Blum, Hubert E, Becker, Gerhild
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2899781/
https://ncbi.nlm.nih.gov/pubmed/20694079
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