Nuclear factor-kappa B decoy suppresses nerve injury and improves mechanical allodynia and thermal hyperalgesia in a rat lumbar disc herniation model

Nuclear factor-kappa B (NF-κB) is a gene transcriptional regulator of inflammatory cytokines. We investigated the transduction efficiency of NF-κB decoy to dorsal root ganglion (DRG), as well as the decrease in nerve injury, mechanical allodynia, and thermal hyperalgesia in a rat lumbar disc herniat...

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Auteurs principaux: Suzuki, Munetaka, Inoue, Gen, Gemba, Takefumi, Watanabe, Tomoko, Ito, Toshinori, Koshi, Takana, Yamauchi, Kazuyo, Yamashita, Masaomi, Orita, Sumihisa, Eguchi, Yawara, Ochiai, Nobuyasu, Kishida, Shunji, Takaso, Masashi, Aoki, Yasuchika, Takahashi, Kazuhisa, Ohtori, Seiji
Format: Artigo
Langue:Inglês
Publié: Springer-Verlag 2009
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2899582/
https://ncbi.nlm.nih.gov/pubmed/19308465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00586-009-0940-x
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