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Influence of Cyclodextrin Complexation with NSAIDs on NSAID/Cold Stress-Induced Gastric Ulceration in Rats

The aim of this work was to study the ability of β-cyclodextrin (β-CD) or hydroxypropyl β-cyclodextrin (HP-β-CD) to ameliorate the induction of gastric ulcers by a nonsteroidal anti-inflammatory drug, indomethacin or piroxicam, in rats exposed to restraint and hypothermic stress at 4 °C. Using oral...

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Main Authors: Alsarra, Ibrahim A., Ahmed, Mahrous O., Alanazi, Fars K., ElTahir, Kamal Eldin Hussein, Alsheikh, Abdulmalik M., Neau, Steven H.
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2899452/
https://ncbi.nlm.nih.gov/pubmed/20617127
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