Metabonomic fingerprints of fasting plasma and spot urine reveal human pre-diabetic metabolic traits

Impaired glucose tolerance (IGT) which precedes overt type 2 diabetes (T2DM) for decades is associated with multiple metabolic alterations in insulin sensitive tissues. In an UPLC-qTOF-mass spectrometry-driven non-targeted metabonomics approach we investigated plasma as well as spot urine of 51 non-...

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Detalhes bibliográficos
Main Authors: Zhao, Xinjie, Fritsche, Jens, Wang, Jiangshan, Chen, Jing, Rittig, Kilian, Schmitt-Kopplin, Philippe, Fritsche, Andreas, Häring, Hans-Ulrich, Schleicher, Erwin D., Xu, Guowang, Lehmann, Rainer
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2899018/
https://ncbi.nlm.nih.gov/pubmed/20676218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-010-0203-1
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