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A novel role of the aryl hydrocarbon receptor (AhR) in centrosome amplification - implications for chemoprevention
BACKGROUND: Centrosome aberrations can cause genomic instability and correlate with malignant progression in common human malignancies such as breast and prostate cancer. Deregulation of cyclin/cyclin-dependent kinase 2 (CDK2) activity has previously been shown to be critically involved in centrosom...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2898706/ https://ncbi.nlm.nih.gov/pubmed/20565777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-153 |
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