A novel role of the aryl hydrocarbon receptor (AhR) in centrosome amplification - implications for chemoprevention

BACKGROUND: Centrosome aberrations can cause genomic instability and correlate with malignant progression in common human malignancies such as breast and prostate cancer. Deregulation of cyclin/cyclin-dependent kinase 2 (CDK2) activity has previously been shown to be critically involved in centrosom...

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Bibliographic Details
Main Authors: Korzeniewski, Nina, Wheeler, Sarah, Chatterjee, Payel, Duensing, Anette, Duensing, Stefan
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898706/
https://ncbi.nlm.nih.gov/pubmed/20565777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-153
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