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Relationships between hypoxia markers and the leptin system, estrogen receptors in human primary and metastatic breast cancer: effects of preoperative chemotherapy

BACKGROUND: Tumor hypoxia is marked by enhanced expression of hypoxia-inducible factor-α (HIF-1α) and glucose transporter-1 (Glut-1). Hypoxic conditions have also been associated with overexpression of angiogenic factors, such as leptin. The aim of our study was to analyze the relationships between...

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Detalhes bibliográficos
Main Authors: Koda, Mariusz, Kanczuga-Koda, Luiza, Sulkowska, Mariola, Surmacz, Eva, Sulkowski, Stanislaw
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898699/
https://ncbi.nlm.nih.gov/pubmed/20569445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-320
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