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Distinct roles of four gelsolin-like domains of Caenorhabditis elegans gelsolin-like protein-1 in actin filament severing, barbed-end capping, and phosphoinositide binding

It is an unconventional gelsolin-related protein with four gelsolin-like (G) domains (G1 to G4), unlike typical gelsolin-related proteins with three or six G domains. GSNL-1 severs actin filaments and caps the barbed end in a calcium-dependent manner similarly to gelsolin. In contrast, GSNL-1 has di...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Zhongmei, Klaavuniemi, Tuula, Ono, Shoichiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898540/
https://ncbi.nlm.nih.gov/pubmed/20392036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100215b
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