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The structures of mutant forms of Hfq from Pseudomonas aeruginosa reveal the importance of the conserved His57 for the protein hexamer organization

The bacterial Sm-like protein Hfq forms homohexamers both in solution and in crystals. The monomers are organized as a continuous β-sheet passing through the whole hexamer ring with a common hydrophobic core. Analysis of the Pseudomonas aeruginosa Hfq (PaeHfq) hexamer structure suggested that solven...

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Autori principali: Moskaleva, Olga, Melnik, Bogdan, Gabdulkhakov, Azat, Garber, Maria, Nikonov, Stanislav, Stolboushkina, Elena, Nikulin, Alexei
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898456/
https://ncbi.nlm.nih.gov/pubmed/20606268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110017331
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