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Modulation of UvrD Helicase Activity by Covalent DNA-Protein Cross-links

UvrD (DNA helicase II) has been implicated in DNA replication, DNA recombination, nucleotide excision repair, and methyl-directed mismatch repair. The enzymatic function of UvrD is to translocate along a DNA strand in a 3′ to 5′ direction and unwind duplex DNA utilizing a DNA-dependent ATPase activi...

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Autors principals: Kumari, Anuradha, Minko, Irina G., Smith, Rebecca L., Lloyd, R. Stephen, McCullough, Amanda K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898412/
https://ncbi.nlm.nih.gov/pubmed/20444702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.078964
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