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R-spondin-1 Is a Novel β-Cell Growth Factor and Insulin Secretagogue
R-spondin-1 (Rspo1) is an intestinal growth factor known to exert its effects through activation of the canonical Wnt (cWnt) signaling pathway and subsequent expression of cWnt target genes. We have detected Rspo1 mRNA in murine islets and the murine MIN6 and βTC β-cell lines, and Rspo1 protein in M...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2898385/ https://ncbi.nlm.nih.gov/pubmed/20442404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.129874 |
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