Dynamics and Mechanism of p130Cas Localization to Focal Adhesions

The docking protein p130Cas is a major Src substrate involved in integrin signaling and mechanotransduction. Tyrosine phosphorylation of p130Cas in focal adhesions (FAs) has been linked to enhanced cell migration, invasion, proliferation, and survival. However, the mechanism of p130Cas targeting to...

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Hlavní autoři: Donato, Dominique M., Ryzhova, Larisa M., Meenderink, Leslie M., Kaverina, Irina, Hanks, Steven K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898362/
https://ncbi.nlm.nih.gov/pubmed/20430882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.091207
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