Smooth and Cardiac Muscle-selective Knock-out of Krüppel-like Factor 4 Causes Postnatal Death and Growth Retardation

Krüppel-like factor 4 (Klf4) is a transcription factor involved in differentiation and proliferation in multiple tissues. We demonstrated previously that tamoxifen-induced deletion of the Klf4 gene in mice accelerated neointimal formation but delayed down-regulation of smooth muscle cell differentia...

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Hauptverfasser: Yoshida, Tadashi, Gan, Qiong, Franke, Aaron S., Ho, Ruoya, Zhang, Jifeng, Chen, Y. Eugene, Hayashi, Matsuhiko, Majesky, Mark W., Somlyo, Avril V., Owens, Gary K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898332/
https://ncbi.nlm.nih.gov/pubmed/20439457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.112482
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