Cell-free Synthesis and Functional Characterization of Sphingolipid Synthases from Parasitic Trypanosomatid Protozoa

The Trypanosoma brucei genome has four highly similar genes encoding sphingolipid synthases (TbSLS1–4). TbSLSs are polytopic membrane proteins that are essential for viability of the pathogenic bloodstream stage of this human protozoan parasite and, consequently, can be considered as potential drug...

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Autors principals: Sevova, Elitza S., Goren, Michael A., Schwartz, Kevin J., Hsu, Fong-Fu, Turk, John, Fox, Brian G., Bangs, James D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Lipids
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898309/
https://ncbi.nlm.nih.gov/pubmed/20457606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.127662
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