Full-Length Hepatitis B Virus Core Protein Packages Viral and Heterologous RNA with Similarly High Levels of Cooperativity

A critical feature of a viral life cycle is the ability to selectively package the viral genome. In vivo, phosphorylated hepatitis B virus (HBV) core protein specifically encapsidates a complex of pregenomic RNA (pgRNA) and viral polymerase; it has been suggested that packaging is specific for the c...

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Bibliographische Detailangaben
Hauptverfasser: Porterfield, J. Zachary, Dhason, Mary Savari, Loeb, Daniel D., Nassal, Michael, Stray, Stephen J., Zlotnick, Adam
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Structure and Assembly
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898219/
https://ncbi.nlm.nih.gov/pubmed/20427522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00586-10
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