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CLIC4 and Schnurri-2: A dynamic duo in TGFβ signaling with broader implications in cellular homeostasis and disease

CLIC4 is a highly conserved, multifunctional member of the chloride intracellular channel family of proteins. The protein is largely cytoplasmic but translocates to the nucleus upon a variety of stimuli including TGFβ, TNFα and etoposide. Nuclear resident CLIC4 causes growth arrest, terminal differe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shukla, Anjali, Yuspa, Stuart H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898211/
https://ncbi.nlm.nih.gov/pubmed/20617112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.1.2.10920
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