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Side-chain Pairing Preferences in the Parallel Coiled-coil Dimer Motif: Insight on Ion-pairing between Core and Flanking Sites
A new strategy for rapid evaluation of sequence-stability relationships in the parallel coiled-coil motif is described. The experimental design relies upon thiol-thioester exchange equilibria, an approach that is particularly well suited to examination of heterodimeric systems. Our model system has...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2898205/ https://ncbi.nlm.nih.gov/pubmed/20465308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja100080q |
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