Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the craniocervical joints of the axial skeleton

Meox1 and Meox2 are two related homeodomain transcription factor genes that together are essential for the development of all somite compartments. Here we show that mice homozygous for Meox1 mutations alone have abnormalities that are restricted to the sclerotome and its derivatives. A prominent and...

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Bibliografiske detaljer
Main Authors: Skuntz, Susan, Mankoo, Baljinder, Nguyen, Minh-Thanh T., Hustert, Elisabeth, Nakayama, Atsuo, Tournier-Lasserve, Elisabeth, Wright, Christopher V.E., Pachnis, Vassilis, Bharti, Kapil, Arnheiter, Heinz
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898144/
https://ncbi.nlm.nih.gov/pubmed/19520072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.06.006
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