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Dendritic Cells in Chronic Mycobacterial Granulomas Restrict Local Anti-Bacterial T Cell Response in a Murine Model

BACKGROUND: Mycobacterium-induced granulomas are the interface between bacteria and host immune response. During acute infection dendritic cells (DCs) are critical for mycobacterial dissemination and activation of protective T cells. However, their role during chronic infection in the granuloma is p...

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Bibliographische Detailangaben
Hauptverfasser: Schreiber, Heidi A., Hulseberg, Paul D., Lee, JangEun, Prechl, Jozsef, Barta, Peter, Szlavik, Nora, Harding, Jeffrey S., Fabry, Zsuzsanna, Sandor, Matyas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897891/
https://ncbi.nlm.nih.gov/pubmed/20625513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011453
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