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Nuclear Factor κB Deficiency Is Associated with Auditory Nerve Degeneration and Increased Noise-Induced Hearing Loss

Degeneration of the spiral ganglion neurons (SGNs) of the auditory nerve occurs with age and in response to acoustic injury. Histopathological observations suggest that the neural degeneration often begins with an excitotoxic process affecting the afferent dendrites under the inner hair cells (IHCs)...

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Detalhes bibliográficos
Main Authors: Lang, Hainan, Schulte, Bradley A., Zhou, Daohong, Smythe, Nancy, Spicer, Samuel S., Schmiedt, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897814/
https://ncbi.nlm.nih.gov/pubmed/16571762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2488-05.2006
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