High-affinity dopamine D(2)/D(3) PET radioligands (18)F-fallypride and (11)C-FLB457: A comparison of kinetics in extrastriatal regions using a multiple-injection protocol

(18)F-Fallypride and (11)C-FLB457 are commonly used PET radioligands for imaging extrastriatal dopamine D(2)/D(3) receptors, but differences in their in vivo kinetics may affect the sensitivity for measuring subtle changes in receptor binding. Focusing on regions of low binding, a direct comparison...

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Bibliographische Detailangaben
Hauptverfasser: Vandehey, Nicholas T, Moirano, Jeffrey M, Converse, Alexander K, Holden, James E, Mukherjee, Jogesh, Murali, Dhanabalan, Nickles, R Jerry, Davidson, Richard J, Schneider, Mary L, Christian, Bradley T
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897717/
https://ncbi.nlm.nih.gov/pubmed/20040928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.270
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