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Critical Role of Airway Macrophages in Modulating Disease Severity during Influenza Virus Infection of Mice

Airway macrophages provide a first line of host defense against a range of airborne pathogens, including influenza virus. In this study, we show that influenza viruses differ markedly in their abilities to infect murine macrophages in vitro and that infection of macrophages is nonproductive and no i...

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Detalles Bibliográficos
Main Authors: Tate, Michelle D., Pickett, Danielle L., van Rooijen, Nico, Brooks, Andrew G., Reading, Patrick C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897615/
https://ncbi.nlm.nih.gov/pubmed/20504924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00291-10
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