PDK1 Regulates Vascular Remodeling and Promotes Epithelial-Mesenchymal Transition in Cardiac Development

One essential downstream signaling pathway of receptor tyrosine kinases (RTKs), such as vascular endothelial growth factor receptor (VEGFR) and the Tie2 receptor, is the phosphoinositide-3 kinase (PI3K)-phosphoinositide-dependent protein kinase 1 (PDK1)-Akt/protein kinase B (PKB) cascade that plays...

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Bibliographische Detailangaben
Hauptverfasser: Feng, Qiuting, Di, Ruomin, Tao, Fang, Chang, Zai, Lu, Shuangshuang, Fan, Wenjing, Shan, Congjia, Li, Xinli, Yang, Zhongzhou
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897563/
https://ncbi.nlm.nih.gov/pubmed/20457809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00420-10
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