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Nox4-Derived H(2)O(2) Mediates Endoplasmic Reticulum Signaling through Local Ras Activation
The unfolded-protein response (UPR) of the endoplasmic reticulum (ER) has been linked to oxidant production, although the molecular details and functional significance of this linkage are poorly understood. Using a ratiometric H(2)O(2) sensor targeted to different subcellular compartments, we demons...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2897542/ https://ncbi.nlm.nih.gov/pubmed/20457808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01445-09 |
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