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Inactivation and Augmentation of the Primary 3-Ketosteroid-Δ(1)- Dehydrogenase in Mycobacterium neoaurum NwIB-01: Biotransformation of Soybean Phytosterols to 4-Androstene- 3,17-Dione or 1,4-Androstadiene-3,17-Dione

3-Ketosteroid-Δ(1)-dehydrogenase, KsdD(M), was identified by targeted gene disruption and augmentation from Mycobacterium neoaurum NwIB-01, a newly isolated strain. The difficulty of separating 4-androstene-3,17-dione (AD) from 1,4-androstadiene-3,17-dione (ADD) is a key bottleneck to the microbial...

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Main Authors: Wei, Wei, Wang, Feng-qing, Fan, Shu-yue, Wei, Dong-zhi
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897432/
https://ncbi.nlm.nih.gov/pubmed/20453136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00448-10
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