Functional Characterization of LcpA, a Surface-Exposed Protein of Leptospira spp. That Binds the Human Complement Regulator C4BP

We have previously shown that pathogenic leptospiral strains are able to bind C4b binding protein (C4BP). Surface-bound C4BP retains its cofactor activity, indicating that acquisition of this complement regulator may contribute to leptospiral serum resistance. In the present study, the abilities of...

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Détails bibliographiques
Auteurs principaux: Barbosa, Angela S., Monaris, Denize, Silva, Ludmila B., Morais, Zenaide M., Vasconcellos, Sílvio A., Cianciarullo, Aurora M., Isaac, Lourdes, Abreu, Patricia A. E.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
Sujets:
Host Response and Inflammation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897400/
https://ncbi.nlm.nih.gov/pubmed/20404075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00279-10
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