Immune Responses to Recombinant Pneumococcal PsaA Antigen Delivered by a Live Attenuated Salmonella Vaccine

Streptococcus pneumoniae is a leading cause of morbidity and mortality among children worldwide and particularly in developing countries. In this study, we evaluated PsaA, a conserved antigen important for S. pneumoniae adhesion to and invasion into nasopharynx epithelia, for its ability to induce p...

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Bibliographic Details
Main Authors: Wang, Shifeng, Li, Yuhua, Shi, Huoying, Scarpellini, Giorgio, Torres-Escobar, Ascencion, Roland, Kenneth L., Curtiss, Roy
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897375/
https://ncbi.nlm.nih.gov/pubmed/20479086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00176-10
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