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Single-Stranded DNA Binding by F TraI Relaxase and Helicase Domains Is Coordinately Regulated

Transfer of conjugative plasmids requires relaxases, proteins that cleave one plasmid strand sequence specifically. The F plasmid relaxase TraI (1,756 amino acids) is also a highly processive DNA helicase. The TraI relaxase activity is located within the N-terminal ∼300 amino acids, while helicase m...

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Bibliographic Details
Main Authors: Dostál, Lubomír, Schildbach, Joel F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897354/
https://ncbi.nlm.nih.gov/pubmed/20435720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00154-10
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