The Pseudomonas aeruginosa Vfr Regulator Controls Global Virulence Factor Expression through Cyclic AMP-Dependent and -Independent Mechanisms

Vfr is a global regulator of virulence factor expression in the human pathogen Pseudomonas aeruginosa. Although indirect evidence suggests that Vfr activity is controlled by cyclic AMP (cAMP), it has been hypothesized that the putative cAMP binding pocket of Vfr may accommodate additional cyclic nuc...

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Main Authors: Fuchs, Erin L., Brutinel, Evan D., Jones, Adriana K., Fulcher, Nanette B., Urbanowski, Mark L., Yahr, Timothy L., Wolfgang, Matthew C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Molecular Biology of Pathogens
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897347/
https://ncbi.nlm.nih.gov/pubmed/20494996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00363-10
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