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The Wild-Type Hepatitis C Virus Core Inhibits Initiation of Antigen-Specific T- and B-Cell Immune Responses in BALB/c Mice

In this study, the effects of wild-type and deletion mutant hepatitis C virus (HCV) core proteins on the induction of immune responses in BALB/c mice were assessed. p2HA-C145-S23, encoding a core protein with the C-terminal 46 amino acids truncated, significantly produced stronger antibody and cellu...

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Main Authors: Zhu, Wenbo, Chang, Yanzi, Wu, Chunchen, Han, Qingxia, Pei, Rongjuan, Lu, Mengji, Chen, Xinwen
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897262/
https://ncbi.nlm.nih.gov/pubmed/20519445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00490-09
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