Experimental determination of translational start sites resolves uncertainties in genomic open reading frame predictions – application to Mycobacterium tuberculosis

Correct identification of translational start sites is important for understanding protein function and transcriptional regulation. The annotated translational start sites contained in genome databases are often predicted using bioinformatics and are rarely verified experimentally, and so are not al...

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Bibliographic Details
Main Authors: Smollett, Katherine L., Fivian-Hughes, Amanda S., Smith, Joanne E., Chang, Anchi, Rao, Tara, Davis, Elaine O.
Format: Artigo
Language:Inglês
Published: Microbiology Society 2009
Subjects:
Genes and Genomes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897130/
https://ncbi.nlm.nih.gov/pubmed/19118359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.022889-0
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