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Caffeinol at the receptor level; Anti-ischemic effect of NMDA receptor blockade is potentiated by caffeine

BACKGROUND AND PURPOSE: Although caffeinol (combination of low dose of caffeine and ethanol) was shown to robustly reduce stroke damage in experimental models and is now in clinical evaluation for treatment of ischemic stroke, little is known about the potential mechanism of its action. METHODS: We...

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Main Authors: Zhao, Xiurong, Strong, Roger, Piriyawat, Paisith, Palusinski, Robert, Grotta, James C., Aronowski, Jaroslaw
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896831/
https://ncbi.nlm.nih.gov/pubmed/20044532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.109.562900
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